Association of performance status, depression, and demographics with advance directive documentation in patients with glioblastoma

In our sample, AD was more likely to be established for patients with advanced disease and specific demographic factors, whereas depression scores did not predict presence or absence of AD. This may indicate that patients with decreased performance status may be more receptive to completing AD than those with better performance status. Alternatively, it could reflect that providers are more likely to approach the subject as their health deteriorates. Patients preparing for neurosurgical intervention might be more receptive to AD completion and ACP discussion than patients in other phases of care. We offer recommendations to promote a more proactive approach to AD so that more patients are prepared by the time their performance status starts to decline.