Exploring the pathogenic mechanisms of dementia risk factors: a task-fMRI study of mild cognitive impairment
Risk factors can abnormally increase brain activity in DMN. Given the close association between amyloid-β (Aβ) deposition and reduced DMN deactivation, these risk factors may elevate DMN activity, thereby facilitate Aβ accumulation in these regions.
Authors
- Yuling Shen (ORCID: https://orcid.org/0000-0003-0026-4826)
- Min Shi (ORCID: https://orcid.org/0000-0001-8265-5307)
- Ying Liu
- Lijun Wang
- Dongdong Yang
- Shanyu Liu
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Sichuan University (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2026-02-24
- DOI
- https://doi.org/10.3389/fnins.2026.1751092
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chengdu University of Traditional Chinese Medicine
- Guangzhou University of Chinese Medicine
- Chengdu University
- Guangzhou University