Formulation-dependent dissolution and bioaccessibility of curcuminoids and (S)-ar-turmerone from eight commercial turmeric extract- and curcumin-containing dietary supplements
Commercial turmeric supplements exhibit substantial limitations in biorelevant disintegration and dissolution. Superior <i>in vitro</i> release is a prerequisite - but not a guarantee - for enhanced systemic exposure, underscoring the need for cautious interpretation of bioavailability claims.
Authors
- Philip W Melchert (ORCID: https://orcid.org/0000-0001-8276-6621)
- Catherine M. Gurley
- Amar Gopal Chittiboyina (ORCID: https://orcid.org/0000-0002-7047-5373)
- John S. Markowitz (ORCID: https://orcid.org/0000-0002-9830-5392)
- Bill J. Gurley (ORCID: https://orcid.org/0000-0001-5377-6388)
- B Avula
- Kumar Katrugunta
- Ikhlas A Khan
Institutions
- University of Mississippi (US)
Publication Details
- Journal
- Pharmaceutical Biology
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1080/13880209.2026.2631826
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00