Pancreatic intraductal papillary mucinous neoplasm with invasive carcinoma and uterine metastasis: a case report

Intraductal papillary mucinous neoplasm (IPMN) with invasive carcinoma is a rare type of pancreatic cancer that has a better prognosis than classic pancreatic infiltrating ductal carcinoma. Most distant metastases occur in the lymph nodes, lungs, liver, and bones at advanced stages. We report a rare case of an IPMN with invasive carcinoma that metastasized to the uterus, resulting in long-term survival after debulking surgery combined with hyperthermic intraperitoneal chemotherapy on a systemic treatment basis. This rare case highlights the need for oncologists and gynecologists to be vigilant regarding these uncommon metastatic diseases and exercise caution in diagnosis. Comprehensive treatments, including debulking surgery, may improve survival.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-24
DOI
https://doi.org/10.3389/fonc.2025.1562588
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Pancreatic intraductal papillary mucinous neoplasm with invasive carcinoma and uterine metastasis: a case report

Yingyun Zhang, Y. Wang, Yixiu Han, Xiaolong Miao et al.
Frontiers in Oncology
Pancreatic and Hepatic Oncology Research
article

Pancreatic intraductal papillary mucinous neoplasm with invasive carcinoma and uterine metastasis: a case report

Yingyun Zhang, Y. Wang, Yixiu Han, Xiaolong Miao, FangHua Li, Yanxia Liu, Yingxue Guo, Feifei Zhao
article en

Abstract

Intraductal papillary mucinous neoplasm (IPMN) with invasive carcinoma is a rare type of pancreatic cancer that has a better prognosis than classic pancreatic infiltrating ductal carcinoma. Most distant metastases occur in the lymph nodes, lungs, liver, and bones at advanced stages. We report a rare case of an IPMN with invasive carcinoma that metastasized to the uterus, resulting in long-term survival after debulking surgery combined with hyperthermic intraperitoneal chemotherapy on a systemic treatment basis. This rare case highlights the need for oncologists and gynecologists to be vigilant regarding these uncommon metastatic diseases and exercise caution in diagnosis. Comprehensive treatments, including debulking surgery, may improve survival.

Frontiers in OncologyVol. 15
Qingdao University (CN), Affiliated Hospital of Qingdao University (CN), Shengli Oilfield Central Hospital (CN)
Qingdao University, Young Scientists Fund
Good health and well-being
Openalex Percentile: Top 43%
Pancreatic and Hepatic Oncology Research
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