Mitochondrial abnormalities in idiopathic inflammatory myopathies

Mitochondrial dysfunction represents a central pathogenic mechanism in IIMs, tightly interwoven with immune-mediated muscle damage. Targeting both inflammatory and mitochondrial pathways may offer more effective and personalised therapeutic strategies for patients with inflammatory myopathies.

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Publication Details

Journal
Clinical and Experimental Rheumatology
Published
2026-02-24
DOI
https://doi.org/10.55563/clinexprheumatol/qctyi2
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
Field-Weighted Citation Impact
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article

Mitochondrial abnormalities in idiopathic inflammatory myopathies

G. Ricci, FRANCESCA TORRI, M Mancuso, Gabriele Siciliano
Clinical and Experimental Rheumatology
Inflammatory Myopathies and Dermatomyositis
article

Mitochondrial abnormalities in idiopathic inflammatory myopathies

G. Ricci, FRANCESCA TORRI, M Mancuso, Gabriele Siciliano
article en

Abstract

Mitochondrial dysfunction represents a central pathogenic mechanism in IIMs, tightly interwoven with immune-mediated muscle damage. Targeting both inflammatory and mitochondrial pathways may offer more effective and personalised therapeutic strategies for patients with inflammatory myopathies.

Clinical and Experimental RheumatologyVol. 44(2)
University of Pisa (IT)
Openalex Percentile: Top 45%
Inflammatory Myopathies and Dermatomyositis
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