The Advanced Integrated Respiratory (AIR) Model: Integration of Air–Liquid Interface Cell Cultures within a Human Airway Model for Inhalation Toxicology
This integrated approach represents a significant advancement in the study of inhaled aerosol deposition, toxicity, and pharmacokinetics, offering a robust tool for predicting lung injury and enhancing the detection of a wide range of inhaled aerosols, including but not limited to toxins.
Authors
- Patrick He (ORCID: https://orcid.org/0000-0003-3446-5490)
- Patrick T. Spicer (ORCID: https://orcid.org/0000-0002-8562-3906)
- Paul Michael Young
- Hui Xin Ong
- Lois Ledo
- Damien Chong
- Vanessa Wilson
- Hanieh Gholizadeh
- Daniela Traini
Institutions
- Fisher College (US)
- Woolcock Institute of Medical Research (AU)
- UNSW Sydney (AU)
- Macquarie University (AU)
Publication Details
- Journal
- Pharmaceutical Research
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1007/s11095-026-04037-z
- Primary Topic
- Inhalation and Respiratory Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- DMTC
- Medical Research Council
- National Health and Medical Research Council