PGK1 Drives Cardiac Hypertrophy by Regulating the Vimentin/PI3K/Akt Pathway
Our findings highlight a critical role for PGK1 in myocardial hypertrophy, with downstream activation of the vimentin/PI3K/Akt/ferroptosis pathway.
Authors
- Yan Jin (ORCID: https://orcid.org/0000-0003-3981-7459)
- Dawei Li (ORCID: https://orcid.org/0000-0001-6967-4968)
- Zhijun Han (ORCID: https://orcid.org/0009-0009-5981-554X)
- Ao-Yuan Zhang
- Bernd Nuernberg
- Xue-Xue Zhu
- Sandra Beer-Hammer
- Hai-Jian Sun
- Gui-Wen Xu
- Ting He
- Le Yang
- Chen-Yang Zhao
- Yi-Fei Li
- Min Wei
- Rui Li
Institutions
- Jiangnan University (CN)
- China Pharmaceutical University (CN)
- PharmacoGenetics (China) (CN)
Publication Details
- Journal
- Circulation Research
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1161/circresaha.125.327173
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00