Global and regional burden of liver cancer attributable to drug use in elderly patients: a 1990–2021 analysis from the GBD study

The escalating burden of liver cancer attributable to drug use in the elderly underscores the "Cumulative Impact of Prolonged Exposure," where the intersection of physiological aging and complex drug use patterns amplifies hepatic risk. Mitigating this crisis requires stratified strategies: prioritizing "Capacity Building" (integrating screening into infectious disease programs) in resource-limited settings, and implementing strict "Stewardship" (pharmacovigilance and active deprescribing) in developed nations to curb this trajectory.