Risk factors associated with non-curative resection and metachronous cancer after endoscopic submucosal dissection in patients with ulcerative early gastric cancer

Lesion size of 20-30 mm and an undifferentiated histologic type on preoperative biopsy were identified as independent risk factors for NCR in patients with ulcerative EGC. In addition, older age and indistinct ulcer margins were significantly associated with an increased risk of MGC following ESD. Careful preoperative evaluation and long-term surveillance are essential for optimizing therapeutic outcomes in ulcerative EGC.