A two-tiered latent class and spatial analytical approach to identify clusters of neonatal mortality among very low birth weight infants: A population-based cohort study
The combined use of LCA and spatial analysis identified distinct patterns of neonatal mortality. LCA differentiated clinically meaningful profiles with specific timing of death, while spatial analysis revealed municipal-level clustering and overlap of these patterns. These findings showed how neonatal mortality is shaped by both diagnostic profiles and territorial context, providing actionable evidence to guide targeted improvements in perinatal and neonatal care to reduce preventable deaths among VLBW infants.
Authors
- Rita de Cássia Xavier Balda (ORCID: https://orcid.org/0000-0002-7553-466X)
- Kelsy Nema Areco
- Adriana Sañudo (ORCID: https://orcid.org/0000-0003-1187-0143)
- Paulo Bandiera‐Paiva (ORCID: https://orcid.org/0000-0001-9409-3970)
- RUTH GUINSBURG
- Túlio Konstantyner (ORCID: https://orcid.org/0000-0002-7931-9692)
- Carlos Roberto Veiga Kiffer (ORCID: https://orcid.org/0000-0003-1122-0693)
- Daniela Testoni (ORCID: https://orcid.org/0000-0001-7629-4904)
- Bernadette Cunha Waldvogel (ORCID: https://orcid.org/0000-0001-5267-7361)
- Ana Sílvia Scavacini Marinonio (ORCID: https://orcid.org/0000-0001-9845-6097)
- Cristiane de Oliveira (ORCID: https://orcid.org/0000-0002-3729-6904)
- Mônica La Porte Teixeira (ORCID: https://orcid.org/0000-0001-7571-8154)
- Rosa Maria Viera Freitas
- Milton Harumi Miyoshi
- Mandira Daripa Kawakami
- Maria Fernanda de Almeida
Institutions
- CNR de la Résistance aux Antibiotiques (FR)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1371/journal.pone.0343004
- Primary Topic
- Maternal and Neonatal Healthcare
- Type
- article
- Field-Weighted Citation Impact
- 0.00