When Fever Defies Diagnosis: Wissler–Fanconi Syndrome as an Atypical Presentation of Adult‐Onset Still's Disease

Adult-onset Still's disease should be considered in young adults presenting with fever of unknown origin and inflammatory arthritis, even in the absence of rash or sore throat. Recognition of the Wissler-Fanconi variant and early ferritin testing can prevent diagnostic delay and enable prompt, effective immunosuppressive therapy.

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Publication Details

Journal
Clinical Case Reports
Published
2026-02-23
DOI
https://doi.org/10.1002/ccr3.72133
Primary Topic
Autoimmune and Inflammatory Disorders Research
Type
article
Field-Weighted Citation Impact
0.00
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article

When Fever Defies Diagnosis: Wissler–Fanconi Syndrome as an Atypical Presentation of Adult‐Onset Still's Disease

Attaina Najeeb, Rahmat Gul Omarzai, Khadija Waleed, Aqsa Abdul Qader et al.
Clinical Case Reports
Autoimmune and Inflammatory Disorders Research
article

When Fever Defies Diagnosis: Wissler–Fanconi Syndrome as an Atypical Presentation of Adult‐Onset Still's Disease

Attaina Najeeb, Rahmat Gul Omarzai, Khadija Waleed, Aqsa Abdul Qader, Salar Sultan, Kamran Taj
article en

Abstract

Adult-onset Still's disease should be considered in young adults presenting with fever of unknown origin and inflammatory arthritis, even in the absence of rash or sore throat. Recognition of the Wissler-Fanconi variant and early ferritin testing can prevent diagnostic delay and enable prompt, effective immunosuppressive therapy.

Clinical Case ReportsVol. 14(3)
Shenyang Medical College (CN), Hunan University of Traditional Chinese Medicine (CN), Polyclinic Medical Center (US), Nangarhar University (AF)
Openalex Percentile: Top 44%
Autoimmune and Inflammatory Disorders Research
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