Functional cycling ergometry with or without electrical stimulation in individuals with secondary progressive multiple sclerosis: A randomized controlled trial
Change in ambulatory function did not differ in participants receiving FES versus passive cycling. Within-group improvement occurred in isolated measures and no adverse events occurred, demonstrating feasibility and acceptability. Longer interventions may be necessary to demonstrate improvements beyond lack of decline, given greater baseline disability in this population.
Authors
- Julie Fiol
- Thomas Shoemaker (ORCID: https://orcid.org/0000-0002-1085-6860)
- Michael Comisac
- Kathleen M. Zackowski (ORCID: https://orcid.org/0000-0002-2399-5704)
- Sandra D. Cassard (ORCID: https://orcid.org/0000-0001-6677-1877)
- Scott D. Newsome
- Jennifer Keller
- Daniel Becker
- Alexandra C. Simpson
Institutions
- Kennedy Krieger Institute (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
Publication Details
- Journal
- Multiple Sclerosis and Related Disorders
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1016/j.msard.2026.107095
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00