Coronary microvascular dysfunction in pregnancy: time to pay closer attention?
Coronary microvascular dysfunction (CMD) is increasingly recognized as a significant cardiovascular condition, particularly among women, yet its diagnosis and management during pregnancy remain poorly understood. CMD may arise <i>de novo</i> in the context of hypertensive disorders of pregnancy or represent an exacerbation of pre-existing endothelial dysfunction. This article views current evidence surrounding CMD in pregnancy, outlines the limitations of current diagnostic and treatment approaches, and highlights critical research gaps that must be addressed to improve outcomes in this vulnerable population.
Authors
- Eirini Beneki (ORCID: https://orcid.org/0000-0002-0464-3607)
- Eirini Dri (ORCID: https://orcid.org/0000-0002-7620-0661)
- Nikolaos Pyrpyris (ORCID: https://orcid.org/0000-0003-0401-9473)
- Kyriakos Dimitriadis (ORCID: https://orcid.org/0000-0003-3186-8905)
- Theodoros Mprotsis (ORCID: https://orcid.org/0000-0003-4713-4244)
- P Iliakis
- Athanasios Sakalidis
- Francesco Perone
- Constantina Aggeli
- Konstantinos Aznaouridis
- Konstantinos Tsioufis
- Aggelos Papanikolaou
Institutions
- National and Kapodistrian University of Athens (GR)
- Biomathematics and Statistics Scotland (GB)
- Applied Biomathematics (United States) (US)
- Magnolia Solar (United States) (US)
- Hippocration General Hospital (GR)
- University of Lausanne (CH)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2026-02-24
- DOI
- https://doi.org/10.3389/fcvm.2026.1734077
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00