Head Growth and Fundoscopy as Proxies for Intracranial Pressure in Metopic Synostosis Treated Surgically vs Conservatively

In this prospective cohort of patients with metopic synostosis, signs of elevated ICP were rare and did not differ between surgical and conservative groups. Although surgery altered head growth trajectories, the low prevalence of ICP-related findings supports close monitoring and selective surgical intervention as safe alternatives to routine surgery.

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Publication Details

Journal
JAMA Network Open
Published
2026-02-24
DOI
https://doi.org/10.1001/jamanetworkopen.2025.59871
Primary Topic
Craniofacial Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Head Growth and Fundoscopy as Proxies for Intracranial Pressure in Metopic Synostosis Treated Surgically vs Conservatively

Marie‐Lise C. van Veelen, Sjoukje E. Loudon, Jochem K. H. Spoor, Dimitris Rizopoulos et al.
JAMA Network Open
Craniofacial Disorders and Treatments
article

Head Growth and Fundoscopy as Proxies for Intracranial Pressure in Metopic Synostosis Treated Surgically vs Conservatively

Marie‐Lise C. van Veelen, Sjoukje E. Loudon, Jochem K. H. Spoor, Dimitris Rizopoulos, Sarah L. Versnel, E Koehoorn, Pauline A. E. Tio, Mieke M. Pleumeekers, Irene M. J. Mathijssen, Lauren I. F. Clement
article en

Abstract

In this prospective cohort of patients with metopic synostosis, signs of elevated ICP were rare and did not differ between surgical and conservative groups. Although surgery altered head growth trajectories, the low prevalence of ICP-related findings supports close monitoring and selective surgical intervention as safe alternatives to routine surgery.

JAMA Network OpenVol. 9(2)
Erasmus MC (NL)
ZonMw
Peace, Justice and strong institutions
Openalex Percentile: Top 43%
Craniofacial Disorders and Treatments
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