Reaction of Diketoesters of Perfluorodicarboxylic Acids with Alkyl Ketones

Diketoesters were obtained by reacting dialkyl esters of perfluoroadipic and perfluoropimelic acids with alkyl ketones. The features of synthesizing polyfluorinated tetraketones via the reaction of dimethyl perfluorododecanedioate with alkyl ketones were studied. It was found that the use of THF increases the yield of tetraketones. Based on the results of non-empirical MP2/6-31G* calculations of possible stages of the process, details of the reaction mechanism were discussed.