Effectiveness of Restylane Lyft for Non-Surgical Full Nose Correction in Chinese Patients: A Retrospective Three-Dimensional Imaging-Based Cohort Study

Abstract Background In Chinese patients, common deficiencies—shortened columella, under-projected tip, and wide alar base—reflect maxillonasal dysplasia. While Restylane Lyft is effective for dorsum augmentation, its role in comprehensive reshaping is less defined. Objectives To assess the efficacy and safety of Restylane Lyft for full nasal contour correction using a modified injection technique targeting the nasal spine and septal structures, evaluated by three-dimensional imaging. Methods Thirty-six patients (32 women, 4 men; mean age 31 years) underwent augmentation with Restylane Lyft. Injections were placed supraperiosteally at the radix, dorsum, and canine fossa, with a deep bolus at the columellar base above the nasal spine and precise deposition between the anterior septal angle and interdomal ligament to elongate the sub-tip lobule. Volumetric and morphologic outcomes were assessed at baseline, 1, 3, 6, and 12 months. Primary endpoints included nasal volume, tip projection, columellar height, and alar width. Satisfaction and adverse events were documented. Results Post-treatment, nasal volume increased +1.2 cm³ and tip projection +2.2 mm, with elongation of +2.5 mm and no widening. At 12 months, improvements persisted (+0.7 cm³, +1.2 mm). Satisfaction was high, with only mild, self-limiting adverse events and no ischemic complications. Conclusions Restylane Lyft, applied through precise anatomical targeting, may offer effective and safe correction of full nasal contours in Chinese patients. Midline bolus at the nasal spine and septal space injections seems to allow for tip projection and lobular elongation without compromising tip definition. More extensive studies need to be conducted to confirm these finding.