Enzyme therapy in a structural light

The paper by Gilski et al. in this issue [IUCrJ (2026), 13, 132-145] focuses on the stereochemical analysis of the catalytic mechanism of asparaginases with the aim of resolving key ambiguities in the mechanism. These enzymes have found truly remarkable therapeutic success in the treatment of childhood leukemias.

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Publication Details

Journal
IUCrJ
Published
2026-02-16
DOI
https://doi.org/10.1107/s2052252526001557
Primary Topic
Enzyme Production and Characterization
Type
article
Field-Weighted Citation Impact
0.00
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article

Enzyme therapy in a structural light

Jon Cooper
IUCrJ
Enzyme Production and Characterization
article

Enzyme therapy in a structural light

Jon Cooper
article en

Abstract

The paper by Gilski et al. in this issue [IUCrJ (2026), 13, 132-145] focuses on the stereochemical analysis of the catalytic mechanism of asparaginases with the aim of resolving key ambiguities in the mechanism. These enzymes have found truly remarkable therapeutic success in the treatment of childhood leukemias.

IUCrJVol. 13(2)
University College London (GB)
Zero hunger
Openalex Percentile: Top 47%
Enzyme Production and Characterization
DOIOpen Access PDFOpenAlex
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