Characterizing pseudoangiomatous stromal hyperplasia ( <scp>PASH</scp> ) of the breast
ER/PR expression in PASH is less frequent than previously reported by some studies. However, the frequency of fat necrosis and associated fibrocystic changes in PASH support a chronic, hormone-related process. Consistent CD34 positivity and absence of markers seen in histologic mimics aid in the diagnosis of PASH in challenging cases. PASH does not appear to impart increased cancer risk.
Authors
- Rahul Koshy
- Pragya Jain (ORCID: https://orcid.org/0000-0001-8139-546X)
- Julie M. Jorns
Institutions
- Medical College of Wisconsin (US)
Publication Details
- Journal
- Histopathology
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1111/his.70127
- Primary Topic
- Breast Lesions and Carcinomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00