Alpha-1-microglobulin in first morning urine. Clinical interest

The first urine sample of the morning can be used to quantify alpha-1-microglobulin due to its good correlation with 24-h urine samples, as well as not being affected by age or gender. A quantification > 7.08 (mg/L)/g creatinine in the first morning urine should raise suspicion of the onset of tubular damage, especially in hypertensive or diabetic patients.

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Publication Details

Journal
Nefrología (English Edition)
Published
2026-02-24
DOI
https://doi.org/10.1016/j.nefroe.2026.501447
Primary Topic
Chronic Kidney Disease and Diabetes
Type
article
Field-Weighted Citation Impact
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article

Alpha-1-microglobulin in first morning urine. Clinical interest

Beatriz Sacristán Enciso, A. Martin, Cristina Xavier Aller, J Carretero Gómez et al.
Nefrología (English Edition)
Chronic Kidney Disease and Diabetes
article

Alpha-1-microglobulin in first morning urine. Clinical interest

Beatriz Sacristán Enciso, A. Martin, Cristina Xavier Aller, J Carretero Gómez, María Carande del Río, Nicolas R. Robles
article en

Abstract

The first urine sample of the morning can be used to quantify alpha-1-microglobulin due to its good correlation with 24-h urine samples, as well as not being affected by age or gender. A quantification > 7.08 (mg/L)/g creatinine in the first morning urine should raise suspicion of the onset of tubular damage, especially in hypertensive or diabetic patients.

Nefrología (English Edition)Vol. 46(3)
Instituto de Arqueología-Mérida (ES), Centro de Implantología Cirugía Oral y Maxilofacial (ES), Universidad de Extremadura (ES)
Good health and well-being
Openalex Percentile: Top 53%
Chronic Kidney Disease and Diabetes
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