Enhanced recovery mitigates sodium-glucose cotransporter-2 inhibitors associated mobility decline in valve surgery patients

SGLT2i use is associated with transient perioperative mobility impairment in VHD patients, evidenced by longer ICU stays and delayed mobilization. However, a structured ERAS protocol effectively mitigates these limitations, facilitating superior functional recovery by discharge. These findings underscore the necessity of adapting or closely monitoring ERAS protocols, particularly for patients on SGLT2i, to mitigate early mobility deficits. This supports tailoring ERAS pathways, particularly early mobilization, for this patient population.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2026-02-24
DOI
https://doi.org/10.3389/fcvm.2026.1746050
Primary Topic
Enhanced Recovery After Surgery
Type
article
Field-Weighted Citation Impact
0.00

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article

Enhanced recovery mitigates sodium-glucose cotransporter-2 inhibitors associated mobility decline in valve surgery patients

Xin Xu, Enkang Lu, Chengyao Xu, Minlai Chen et al.
Frontiers in Cardiovascular Medicine
Enhanced Recovery After Surgery
article

Enhanced recovery mitigates sodium-glucose cotransporter-2 inhibitors associated mobility decline in valve surgery patients

Xin Xu, Enkang Lu, Chengyao Xu, Minlai Chen, Hao You, Xuezhou Zhang, Yong Sun, Xia Zhao
article en

Abstract

SGLT2i use is associated with transient perioperative mobility impairment in VHD patients, evidenced by longer ICU stays and delayed mobilization. However, a structured ERAS protocol effectively mitigates these limitations, facilitating superior functional recovery by discharge. These findings underscore the necessity of adapting or closely monitoring ERAS protocols, particularly for patients on SGLT2i, to mitigate early mobility deficits. This supports tailoring ERAS pathways, particularly early mobilization, for this patient population.

Frontiers in Cardiovascular MedicineVol. 13
Shanghai University of Sport (CN), Zhongshan Hospital of Xiamen University (CN)
Shanghai University of Sport, Xiamen University
Openalex Percentile: Top 46%
Enhanced Recovery After Surgery
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