Morphological analysis of posterior fossa in Apert and Crouzon syndromes before and after posterior cranial vault expansion

While PCVE increased posterior fossa volume, it did not appear to improve posterior fossa shape in either Apert or Crouzon patients. Future studies are required to address the limitations of small sample sizes, lack of post-operative data on Chiari anomaly, and surgical variability to further explore possible correlations between the aforementioned parameters.

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Publication Details

Journal
Journal of Cranio-Maxillofacial Surgery
Published
2026-02-25
DOI
https://doi.org/10.1016/j.jcms.2026.104523
Primary Topic
Craniofacial Disorders and Treatments
Type
article
Field-Weighted Citation Impact
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article

Morphological analysis of posterior fossa in Apert and Crouzon syndromes before and after posterior cranial vault expansion

Mehran Moazen, Ce Liang, Susan E. Evans, Wuyang Shui et al.
Journal of Cranio-Maxillofacial Surgery
Craniofacial Disorders and Treatments
article

Morphological analysis of posterior fossa in Apert and Crouzon syndromes before and after posterior cranial vault expansion

Mehran Moazen, Ce Liang, Susan E. Evans, Wuyang Shui, Roman Hossein Khonsari, Christian A. Duncan, Ruonan Dong, David Johnson, Giovanna Paternoster
article en

Abstract

While PCVE increased posterior fossa volume, it did not appear to improve posterior fossa shape in either Apert or Crouzon patients. Future studies are required to address the limitations of small sample sizes, lack of post-operative data on Chiari anomaly, and surgical variability to further explore possible correlations between the aforementioned parameters.

Journal of Cranio-Maxillofacial SurgeryVol. 54(6)
Hôpital Necker-Enfants Malades (FR), University of Liverpool (GB), University of Oxford (GB), The London College (GB), Oxford BioMedica (United Kingdom) (GB), Alder Hey Children's Hospital (GB), University College London (GB)
Openalex Percentile: Top 43%
Craniofacial Disorders and Treatments
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