Characteristics of monogenic inflammatory bowel disease in very early-onset cases: a Japanese multicenter registry study
Patients with VEO-IBD who present an IBD-U phenotype and have a history of severe infections during infancy should be prioritized for genetic analysis to investigate the possibility of monogenic IBD.
Authors
- Nao Tachibana
- Natsuki Ito (ORCID: https://orcid.org/0000-0002-6415-9753)
- Sawako Kato (ORCID: https://orcid.org/0000-0002-6364-2583)
- Keisuke Jimbo (ORCID: https://orcid.org/0000-0001-6317-4305)
- Fumihiko Kakuta (ORCID: https://orcid.org/0000-0003-4064-0937)
- Mikihiro Inoue (ORCID: https://orcid.org/0000-0003-4573-0405)
- Ryusuke Nambu (ORCID: https://orcid.org/0000-0002-7206-7111)
- Eitaro Hiejima (ORCID: https://orcid.org/0000-0002-6663-6656)
- Tatsuki Mizuochi (ORCID: https://orcid.org/0000-0002-2943-7068)
- Naomi Iwata
- Shigeo Nishimata
- T Ishige
- H Kumagai
- T Kudo
- S I Hagiwara
- Toshiaki Shimizu
- Japanese Pediatric Inflammatory Bowel Disease Registry (JPIBD-R)
- Hitoshi Tajiri
- Katsuhiro Arai
- Mika Sasaki
- Yuri Hirano
- Hirotaka Shimizu
- Takeshi Saito
Institutions
- Kurume University (JP)
- Shinshu University (JP)
- Fujita Health University (JP)
- Jichi Medical University (JP)
- Tokyo Medical University (JP)
- Gunma University (JP)
- Iwate Medical University (JP)
- Osaka Prefectural Medical Center (JP)
- Juntendo University (JP)
- Miyagi Children's Hospital (JP)
- Osaka Women's and Children's Hospital (JP)
- Saitama Children's Medical Center (JP)
- Okinawa Prefectural Chubu Hospital (JP)
- National Center For Child Health and Development (JP)
- Chiba Hospital (JP)
- National Hospital Organization (JP)
- Tokyo Metropolitan Children's Medical Center (JP)
- Kyoto University Hospital (JP)
Publication Details
- Journal
- Intestinal Research
- Published
- 2026-02-24
- DOI
- https://doi.org/10.5217/ir.2025.00203
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Center for Child Health and Development