Sotatercept for the treatment of portopulmonary hypertension: a case report

This report demonstrates tolerability and efficacy of Sotatercept in portopulmonary hypertension, identifies candidate biomarkers of treatment response, but also suggests caution may be warranted. Findings from this work support further investigation of Sotatercept in the treatment of portopulmonary hypertension.

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Publication Details

Journal
Communications Medicine
Published
2026-02-24
DOI
https://doi.org/10.1038/s43856-026-01452-6
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Sotatercept for the treatment of portopulmonary hypertension: a case report

William J. Zacharias, Arun Jose, Marina Yasnogorodsky, Assem Ziady et al.
Communications Medicine
Pulmonary Hypertension Research and Treatments
article

Sotatercept for the treatment of portopulmonary hypertension: a case report

William J. Zacharias, Arun Jose, Marina Yasnogorodsky, Assem Ziady, Sharlene Fernandes, Jean Elwing
article en

Abstract

This report demonstrates tolerability and efficacy of Sotatercept in portopulmonary hypertension, identifies candidate biomarkers of treatment response, but also suggests caution may be warranted. Findings from this work support further investigation of Sotatercept in the treatment of portopulmonary hypertension.

Communications Medicine
Cincinnati Children's Hospital Medical Center (US), University of Cincinnati (US)
Good health and well-being
Openalex Percentile: Top 45%
Pulmonary Hypertension Research and Treatments
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