Increased Serum Neurofilament Light Chain Levels in Parkinson's Disease Patients Carrying the p. <scp> A53T <i>SNCA</i> </scp> Mutation: Data from the Parkinson's Progression Markers Initiative Study

A53T-PD patients have high NfL levels, which could potentially be used as an outcome in clinical trials with disease-modifying agents. © 2026 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

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Publication Details

Journal
Movement Disorders
Published
2026-02-23
DOI
https://doi.org/10.1002/mds.70236
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Increased Serum Neurofilament Light Chain Levels in Parkinson's Disease Patients Carrying the p. A53T SNCA Mutation: Data from the Parkinson's Progression Markers Initiative Study

Nikolaos Papagiannakis, Christos Koros, Athina-Maria Simitsi, Leonidas Stefanis et al.
Movement Disorders
Parkinson's Disease Mechanisms and Treatments
article

Increased Serum Neurofilament Light Chain Levels in Parkinson's Disease Patients Carrying the p. A53T SNCA Mutation: Data from the Parkinson's Progression Markers Initiative Study

Nikolaos Papagiannakis, Christos Koros, Athina-Maria Simitsi, Leonidas Stefanis, and The Parkinson's Progression Markers Initiative
article en

Abstract

A53T-PD patients have high NfL levels, which could potentially be used as an outcome in clinical trials with disease-modifying agents. © 2026 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Movement Disorders
National and Kapodistrian University of Athens (GR), Eginition Hospital (GR)
Partnerships for the goals
Openalex Percentile: Top 50%
Parkinson's Disease Mechanisms and Treatments
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