Five new cassane diterpenoids from the seeds of <i>Pterolobium macropterum</i>
Five undescribed cassane diterpenoids were obtained from the seeds of <i>Pterolobium macropterum</i>. Their structures were established through extensive 1D and 2D NMR spectroscopy, and mass spectrometry. Their absolute configurations were assigned by electronic circular dichroism spectrum. Compounds <b>1</b> and <b>3</b> exhibited cytotoxic effects for the human glioma U251 cells with IC<sub>50</sub> values of 28.48 ± 2.7 and 14.43 ± 7.8 <i>μ</i>M, respectively.
Authors
- Puzhao Zhang (ORCID: https://orcid.org/0000-0001-9907-0989)
- Gang Ke (ORCID: https://orcid.org/0000-0003-1813-5985)
- Ren-Geng Shu
- Yue-ping Lan
- Yi-Hui Li
- En Yuan
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Bozhou People's Hospital (CN)
Publication Details
- Journal
- Journal of Asian Natural Products Research
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1080/10286020.2026.2625943
- Primary Topic
- Biological Stains and Phytochemicals
- Type
- article
- Field-Weighted Citation Impact
- 0.00