Risk of Heart Failure Hospitalization for GLP-1 Receptor Agonists Versus DPP-4 Inhibitors or SGLT-2 Inhibitors in Patients With Type 2 Diabetes: A Target Trial Emulation
GLP-1RA use is associated with a lower risk of HHF compared with DPP-4i and similar risks compared with SGLT-2i in routine clinical care for patients with type 2 diabetes.
Authors
- Dongze Ji (ORCID: https://orcid.org/0000-0002-9701-3638)
- Yan Xu (ORCID: https://orcid.org/0000-0003-0379-8866)
- Edouard L Fu
- Katherine R. Tuttle
- Juan-Jesus Carrero
- Tao Huang
- Yue Zhang
Institutions
- Providence Regional Medical Center Everett (US)
- Peking University (CN)
- Leiden University Medical Center (NL)
- Inland Northwest Health Services (US)
- Danderyds sjukhus (SE)
- Karolinska Institutet (SE)
- Institute of Translational Health Sciences (US)
- Providence Health & Services (US)
Publication Details
- Journal
- Circulation
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1161/circulationaha.125.075157
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00