Elevated gamma spectral event peak power during auditory chirp is associated with neuropsychiatric features in Fragile X syndrome
Identifying a tonic elevation of gamma event peak power in FXS during auditory processing suggests altered neural circuit mechanisms underlying aberrant gamma activity. This provides a more direct basis for understanding auditory hypersensitivity, fostering opportunities for back translation and targeted treatment development.
Authors
- Elizabeth Blank
- Paul S. Horn (ORCID: https://orcid.org/0000-0002-4990-5754)
- Ernest V. Pedapati (ORCID: https://orcid.org/0000-0002-7954-5104)
- Grace Westerkamp
- Lauren E. Ethridge (ORCID: https://orcid.org/0000-0003-0601-6911)
- Y. Liu (ORCID: https://orcid.org/0009-0004-1340-0545)
- Stephanie R. Jones (ORCID: https://orcid.org/0000-0001-6760-5301)
- Makoto Miyakoshi (ORCID: https://orcid.org/0000-0002-4062-6679)
- Ryan Thorpe (ORCID: https://orcid.org/0000-0003-2491-8599)
- Peyton Siekierski (ORCID: https://orcid.org/0009-0000-9681-5746)
- Lisa A. De Stefano
- Craig Erickson
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- Brown University (US)
- University of Oklahoma Health Sciences Center (US)
- University of Oklahoma (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Clinical Neurophysiology
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1016/j.clinph.2026.2111713
- Primary Topic
- Genetics and Neurodevelopmental Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00