MCI detection from handwritten drawing test using residual vision transformer

Mild Cognitive Impairment (MCI) is a clinical condition characterized by noticeable cognitive decline that is greater than expected for an individual’s age, yet not severe enough to interfere significantly with daily life. Early detection of MCI is critical, as it offers the opportunity to intervene before progression to more severe neurodegenerative diseases such as Alzheimer’s. While traditional diagnostic methods such as the Clock Drawing Test, Trail Making Test, and Cube Copying Test are widely used by clinicians, their manual assessment process can be subjective and time-consuming. This research addresses the automation of MCI detection using deep learning techniques applied to these neuro-psychological drawing tasks. A hybrid deep learning architecture—ResViT, which integrates ResNet50 for local feature extraction and a Vision Transformer (ViT) for capturing global context within the drawings, is being proposed. The ResViT architecture showed improved generalization and robustness across test cases, achieving a classification accuracy of 74.09% and an F1 score of 0.6716. Our results demonstrate that integrating Vision Transformer and ResNet architectures into a unified hybrid model enhances performance in cognitive disorder classification tasks, offering more accurate and measurable outcomes for early dementia detection through neuropsychological screening tools.

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Publication Details

Journal
Scientific Reports
Published
2026-02-24
DOI
https://doi.org/10.1038/s41598-026-40716-y
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00

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article

MCI detection from handwritten drawing test using residual vision transformer

Irum Matloob, Aliya Ashraf, Hessa Alfraihi, Faiza Syed et al.
Scientific Reports
Dementia and Cognitive Impairment Research
article

MCI detection from handwritten drawing test using residual vision transformer

Irum Matloob, Aliya Ashraf, Hessa Alfraihi, Faiza Syed, Ayesha Tayyabah, Mehreen Sirshar
article en

Abstract

Mild Cognitive Impairment (MCI) is a clinical condition characterized by noticeable cognitive decline that is greater than expected for an individual’s age, yet not severe enough to interfere significantly with daily life. Early detection of MCI is critical, as it offers the opportunity to intervene before progression to more severe neurodegenerative diseases such as Alzheimer’s. While traditional diagnostic methods such as the Clock Drawing Test, Trail Making Test, and Cube Copying Test are widely used by clinicians, their manual assessment process can be subjective and time-consuming. This research addresses the automation of MCI detection using deep learning techniques applied to these neuro-psychological drawing tasks. A hybrid deep learning architecture—ResViT, which integrates ResNet50 for local feature extraction and a Vision Transformer (ViT) for capturing global context within the drawings, is being proposed. The ResViT architecture showed improved generalization and robustness across test cases, achieving a classification accuracy of 74.09% and an F1 score of 0.6716. Our results demonstrate that integrating Vision Transformer and ResNet architectures into a unified hybrid model enhances performance in cognitive disorder classification tasks, offering more accurate and measurable outcomes for early dementia detection through neuropsychological screening tools.

Scientific ReportsVol. 16(1)
Princess Nourah bint Abdulrahman University (SA), Fatima Jinnah Women University (PK)
Princess Nourah Bint Abdulrahman University
Openalex Percentile: Top 50%
Dementia and Cognitive Impairment Research
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