Ameliorative effects of melatonin on radiotherapy-induced apoptotic and inflammatory responses in rat parotid gland
Melatonin effectively mitigates key apoptotic, inflammatory, and angiogenic responses associated with radiation-induced parotid gland injury. These findings support melatonin as a potential radioprotective adjunct during head-and-neck irradiation.
Authors
- Fatih Hacımustafaoğlu
- Yalçın Erzurumlu (ORCID: https://orcid.org/0000-0001-6835-4436)
- Serhat Aras (ORCID: https://orcid.org/0000-0002-4825-5921)
- Burcu Çaykara (ORCID: https://orcid.org/0000-0001-7063-2140)
Institutions
- Süleyman Demirel Üniversitesi (TR)
- Haydarpaşa Numune Eğitim ve Araştırma Hastanesi (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- University of Health Sciences Antigua (AG)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1186/s12903-026-07966-8
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 0.00