Complete clinical and serological remission of anti-synthetase syndrome after autologous haematopoietic stem cell transplantation

Letters to the Editors Complete clinical and serological remission of anti-synthetase syndrome after autologous haematopoietic stem cell transplantationSirs, Anti-synthetase syndrome (ASS) is a chronic, rare, systemic autoimmune rheumatic disease.It is typically characterised by the presence of autoantibodies against different aminoacyl-transfer RNA synthetase (ARS), along with a range of clinical manifestations, including arthritis, myositis, skin involvement, and interstitial lung disease (ILD), among others (1).Management of ASS is often challenging due to disease heterogeneity, limited scientific evidence for treatment, and the lack of standardised guidelines (2).Long-term treatment is generally required.Severe cases carry an uncertain prognosis, although stabilisation or improvement is achievable.ILD progression