Evidence Review for Centers for Disease Control and Prevention Guidance Development on the Detection of <i>Chlamydia trachomatis</i> and <i>Neisseria gonorrhoeae</i>

This supplement review article discusses recent advancements in Chlamydia trachomatis and Neisseria gonorrhoeae detection methods, addressing key questions related to laboratory-based molecular methods, point-of-care testing, culture, and resistance detection. Each manuscript in this supplement summarizes available test methods and their performance characteristics. Additionally, current challenges and research gaps are described. Emerging technologies, such as molecular point-of-care tests and self-collection kits, are highlighted for their potential to improve accessibility, accuracy, and patient-centered care.