Association of G-Protein-Coupled Receptors autoantibodies with vasoregulation in Post-COVID
GPCR autoantibodies were highly prevalent in this Post-COVID cohort. Several GPCR autoantibodies were associated with measures of vasorelaxation like lower systolic and diastolic aortic blood pressure and stronger endothelium-dependent vasodilation. However, given the absence of differences in microvascular and macrovascular function, the precise role of GPCR autoantibodies remains elusive.
Authors
- Oliver Sander (ORCID: https://orcid.org/0000-0001-5196-9370)
- Ulrik Stervbo (ORCID: https://orcid.org/0000-0002-2831-8868)
- Sebastian Bertram (ORCID: https://orcid.org/0000-0003-4516-6840)
- Maximilian Seidel (ORCID: https://orcid.org/0000-0003-0029-8663)
- Nina Babel
- Lea Wiemers
- Westhoff TH
- Felix S. Seibert
- Monika Segelbacher
- Melisa Kurucay
Institutions
- University Hospitals of the Ruhr-University of Bochum (DE)
- Universitätsklinik Marien Hospital Herne (DE)
- Düsseldorf University Hospital (DE)
- Marien Hospital Witten (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1371/journal.pone.0343264
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00