Effects of swinging exercise on immune biomarkers: a systematic review and meta-analysis with machine learning-based identification of responder profiles

Swinging exercise induces a <i>dual immune response</i>: transient T-cell suppression coupled with enhanced humoral immunity. The inter-individual variability highlights the need for personalized training regimens based on immune monitoring. We recommend integrating immune profiling into athletic programming to optimize health and performance outcomes. The observed increase in markers of muscle damage and metabolic stress (CK, LDH, and BUN) confirms the substantial physiological stimulus provided by these sports.

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Publication Details

Journal
Frontiers in Physiology
Published
2026-02-24
DOI
https://doi.org/10.3389/fphys.2025.1694645
Primary Topic
Exercise and Physiological Responses
Type
article
Field-Weighted Citation Impact
0.00

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article

Effects of swinging exercise on immune biomarkers: a systematic review and meta-analysis with machine learning-based identification of responder profiles

Wei Cheng Siang, Xie Yanli, Zhang Guodong
Frontiers in Physiology
Exercise and Physiological Responses
article

Effects of swinging exercise on immune biomarkers: a systematic review and meta-analysis with machine learning-based identification of responder profiles

Wei Cheng Siang, Xie Yanli, Zhang Guodong
article en

Abstract

Swinging exercise induces a <i>dual immune response</i>: transient T-cell suppression coupled with enhanced humoral immunity. The inter-individual variability highlights the need for personalized training regimens based on immune monitoring. We recommend integrating immune profiling into athletic programming to optimize health and performance outcomes. The observed increase in markers of muscle damage and metabolic stress (CK, LDH, and BUN) confirms the substantial physiological stimulus provided by these sports.

Frontiers in PhysiologyVol. 16
Shanxi Agricultural University (CN)
Shanxi Agricultural University
Openalex Percentile: Top 45%
Exercise and Physiological Responses
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