Toripalimab-based chemoimmunotherapy for unresectable sinonasal NUT carcinoma of the maxillary sinus: a case report
To our knowledge, this is the first reported case of toripalimab-based chemoimmunotherapy demonstrating an early partial response and short-term disease control in unresectable maxillary sinus NUT carcinoma. It supports the potential role of PD-1 blockade integrated with platinum-taxane chemotherapy as a component of multimodal management for sinonasal NUT carcinomas.
Authors
- Ling Lin (ORCID: https://orcid.org/0000-0001-5527-0575)
- Jian Liang Tan (ORCID: https://orcid.org/0000-0002-1083-8259)
- Xinglong Wang (ORCID: https://orcid.org/0000-0001-8046-3539)
- Dan Yu (ORCID: https://orcid.org/0000-0002-3112-2292)
- Bei Guo
- Yonghui Xie
Institutions
- Central Hospital of Wuhan (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-24
- DOI
- https://doi.org/10.3389/fimmu.2026.1763340
- Primary Topic
- Protein Degradation and Inhibitors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Hubei Province