Rapid and reagent-free screening of occult hepatitis B virus infection based on plasma Vis-NIR spectral pattern recognition
These results indicated that Vis-NIR spectroscopy pattern recognition can accurately discriminate between OBI and normal controls' plasma samples. This method is reagent-free, rapid, and simple, making it suitable for large-scale, low-cost rapid screening of OBI. In particular, the proposed few-wavelength model can provide an important reference for the development of small specialized blood analyzers for OBI detection.
Authors
- Lining Huang (ORCID: https://orcid.org/0000-0003-1177-4530)
- Min Chen (ORCID: https://orcid.org/0000-0002-2149-5933)
- Huanjie Zhou
- Chao Ou (ORCID: https://orcid.org/0000-0003-2541-5694)
- Jingjing Xia
- Baoren He
- Linbin Huang
- Meijun Chen
- Qiuhong Mo
- Tao Pan
Institutions
- Guangxi Medical University (CN)
- Integrated Optoelectronics (Norway) (NO)
- Blood Center of Zhejiang Province (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2026-02-23
- DOI
- https://doi.org/10.3389/fbioe.2026.1774782
- Primary Topic
- Spectroscopy and Chemometric Analyses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Wu Jieping Medical Foundation
- Division of Graduate Education