Anticholinergic burden interacts with age and AIDS history to amplify frailty in people with HIV
ACB is a modifiable contributor to frailty in people with HIV, with disproportionate impact on older individuals and those with prior severe immunosuppression. Incorporating routine ACB assessment and deprescribing strategies into HIV care may help support functional ageing and reduce vulnerability.
Authors
- Samuele Gardin
- A. Favaro
- Jacopo Farina (ORCID: https://orcid.org/0009-0003-9198-2600)
- Davide Leoni
- Mattia Trunfio (ORCID: https://orcid.org/0000-0001-8663-719X)
- Giuseppe Sergi
- Annamaria Cattelan
- Lorenza Barbison
- Vincenzo Scaglione
- Maria Mazzitelli
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Padua (IT)
- Agostino Gemelli University Polyclinic (IT)
- University of California System (US)
- University of California San Diego (US)
Publication Details
- Journal
- British Journal of Clinical Pharmacology
- Published
- 2026-02-22
- DOI
- https://doi.org/10.1002/bcp.70504
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00