Gut microbiota and bone aging: Focusing on the gut-X axis modes
This review presents crucial role and regulatory significance of gut-X axis modes in common bone-aging related diseases. By anchoring the gut-X axis as intervention targets, the thinking of gut microbiota and its related metabolites in basic studies and clinical prevention and treatment of bone aging-related diseases might be expanded, and its clinical application transformation and development could be innovated.
Authors
- Qirong Zhou
- Jiacan Su (ORCID: https://orcid.org/0000-0001-7080-263X)
- Yan Wu
- Peng Wang
- Rui-Yang Li
Institutions
- Shanghai University (CN)
- XinHua Hospital (CN)
- Shanghai Institutes for Biological Sciences (CN)
Publication Details
- Journal
- Journal of Orthopaedic Translation
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1016/j.jot.2026.101064
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation