Somatic mutations in cervicovaginal samples: assessing their role in ovarian cancer detection and prognosis

DNA somatic variants in cervicovaginal samples have limited diagnostic value for detecting ovarian cancer. However, their presence may have prognostic significance, warranting further investigation. Future research could explore multimodal strategies that integrate molecular markers with imaging or other approaches to improve early detection.

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Publication Details

Journal
Translational Oncology
Published
2026-02-23
DOI
https://doi.org/10.1016/j.tranon.2026.102712
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Somatic mutations in cervicovaginal samples: assessing their role in ovarian cancer detection and prognosis

Marta López-Querol, Eduard Dorca, Lara Pijuán, Beatriz Pelegrina et al.
Translational Oncology
Ovarian cancer diagnosis and treatment
article

Somatic mutations in cervicovaginal samples: assessing their role in ovarian cancer detection and prognosis

Marta López-Querol, Eduard Dorca, Lara Pijuán, Beatriz Pelegrina, Fátima Marín, Sònia Paytubi, Yolanda Jesus Mendieta Benavente, José Manuel Martínez, Brunet Joan, Jordi Ponce, August Vidal, Laia Alemany, Marc Barahona, Yolanda Pérez-Escanilla, Jon Frias-Gomez, Irene Onieva, Claudia Pavon-Diaz, Laura Costas, Sergi Fernandez-Gonzalez
article en

Abstract

DNA somatic variants in cervicovaginal samples have limited diagnostic value for detecting ovarian cancer. However, their presence may have prognostic significance, warranting further investigation. Future research could explore multimodal strategies that integrate molecular markers with imaging or other approaches to improve early detection.

Translational OncologyVol. 66
Bellvitge University Hospital (ES), Hospital Universitari Arnau de Vilanova (ES), Institut d'Investigació Biomédica de Bellvitge (ES), Institut Català d'Oncologia (ES), Centro de Investigación Biomédica en Red de Cáncer (ES)
Good health and well-being
Openalex Percentile: Top 41%
Ovarian cancer diagnosis and treatment
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