Monochorionic diamniotic twin brothers with severe hemophilia A: a case report

The coagulation system is not fully developed at birth, complicating clinical decision-making and the correct interpretation of coagulation testing. Targeted coagulation profiling and factor assays are mission-critical for newborns from twin pregnancies when a hematological disorder is suspected. Coagulation factor assays are essential to confirm the diagnosis of hemophilia A. An early diagnosis of hemophilia is crucial for the timely initiation of an appropriate management plan.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2026-02-23
DOI
https://doi.org/10.3389/fped.2026.1770910
Primary Topic
Hemophilia Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Monochorionic diamniotic twin brothers with severe hemophilia A: a case report

Lorenzo Riboldi, Alessandra Coscia, Chiara Peila
Frontiers in Pediatrics
Hemophilia Treatment and Research
article

Monochorionic diamniotic twin brothers with severe hemophilia A: a case report

Lorenzo Riboldi, Alessandra Coscia, Chiara Peila
article en

Abstract

The coagulation system is not fully developed at birth, complicating clinical decision-making and the correct interpretation of coagulation testing. Targeted coagulation profiling and factor assays are mission-critical for newborns from twin pregnancies when a hematological disorder is suspected. Coagulation factor assays are essential to confirm the diagnosis of hemophilia A. An early diagnosis of hemophilia is crucial for the timely initiation of an appropriate management plan.

Frontiers in PediatricsVol. 14
Department of Public Health (US)
Good health and well-being
Openalex Percentile: Top 45%
Hemophilia Treatment and Research
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