Chronic sequelae of immune-related adverse events

While acute management of irAEs has improved over the past decade, there is a major gap in understanding and addressing their chronic sequelae. Challenges in studying these sequelae include the complexity of cancer care, overlapping clinical presentations, and previously, a lack of long-term data. Continued research from large multicenter studies and dedicated databases can identify high-risk patients, inform risk-benefit discussions, refine management strategies, and pave the way for evidence-based, long-term care.

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Publication Details

Journal
Expert Opinion on Drug Safety
Published
2026-02-24
DOI
https://doi.org/10.1080/14740338.2026.2635994
Primary Topic
Fibromyalgia and Chronic Fatigue Syndrome Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Chronic sequelae of immune-related adverse events

Sean Ngo, AJAY SHESHADRI, E. Roeland, Ata S. Moshiri et al.
Expert Opinion on Drug Safety
Fibromyalgia and Chronic Fatigue Syndrome Research
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Chronic sequelae of immune-related adverse events

Sean Ngo, AJAY SHESHADRI, E. Roeland, Ata S. Moshiri, Carolina Colli Cruz, Thein Hlaing Oo, Faraz Jafri, Pauline Funchain, Rachel Mortan, Stephanie Kim, Hao Chi Zhang, Raakhi Menon, Tomas G. Neilan, Andres Urias Rivera, Anirudha Chatterjee, Devin M. Garza, Jarrett Rong, Hamza Salim, Marc Ernstoff
article en

Abstract

While acute management of irAEs has improved over the past decade, there is a major gap in understanding and addressing their chronic sequelae. Challenges in studying these sequelae include the complexity of cancer care, overlapping clinical presentations, and previously, a lack of long-term data. Continued research from large multicenter studies and dedicated databases can identify high-risk patients, inform risk-benefit discussions, refine management strategies, and pave the way for evidence-based, long-term care.

Expert Opinion on Drug Safety
National Institutes of Health (US), The University of Texas MD Anderson Cancer Center (US), Oregon Health & Science University (US), Baylor College of Medicine (US), Massachusetts General Hospital (US), Stanford Medicine (US), The University of Texas Health Science Center (US), The University of Texas Medical Branch at Galveston (US), New York University (US), The University of Texas Health Science Center at Houston (US)
Openalex Percentile: Top 51%
Fibromyalgia and Chronic Fatigue Syndrome Research
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