Trends in Unprotected Left Main Percutaneous Coronary Intervention and Clinical Outcomes

In a nationwide Japanese PCI registry, unprotected LM PCI consistently accounted for 5% of PCI procedures. Although unadjusted in-hospital mortality rose modestly over time, the findings indicate this was largely explained by increasing patient complexity, with risk-adjusted outcomes remaining stable, supporting the continued role of LM PCI as a safe revascularization option in contemporary practice.

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Publication Details

Journal
JAMA Network Open
Published
2026-02-23
DOI
https://doi.org/10.1001/jamanetworkopen.2025.60422
Primary Topic
Coronary Interventions and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00

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article

Trends in Unprotected Left Main Percutaneous Coronary Intervention and Clinical Outcomes

Nobuhiro Ikemura, Yuichiro Mori, Shun Kohsaka, Ken Kozuma et al.
JAMA Network Open
Coronary Interventions and Diagnostics
article

Trends in Unprotected Left Main Percutaneous Coronary Intervention and Clinical Outcomes

Nobuhiro Ikemura, Yuichiro Mori, Shun Kohsaka, Ken Kozuma, T Amano, J A Spertus, David J. Cohen, Paul S. Chan
article en

Abstract

In a nationwide Japanese PCI registry, unprotected LM PCI consistently accounted for 5% of PCI procedures. Although unadjusted in-hospital mortality rose modestly over time, the findings indicate this was largely explained by increasing patient complexity, with risk-adjusted outcomes remaining stable, supporting the continued role of LM PCI as a safe revascularization option in contemporary practice.

JAMA Network OpenVol. 9(2)
Aichi Medical University (JP), Keio University (JP), Kyoto University (JP), Health Innovations (United States) (US), St. Francis Hospital (US), Teikyo University Hospital (JP), Saint Luke's Hospital (US), Cardiovascular Research Foundation (US)
Japan Society for the Promotion of Science
Good health and well-being
Openalex Percentile: Top 46%
Coronary Interventions and Diagnostics
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