Distinct Subdivisions of the Cingulo-Insular Region and Their Role in Modulating the Cardiac Sympathetic-Parasympathetic Balance

Within the cingulo-insular region, the anterior cingulate gyrus is associated with a relative cardio-parasympathetic dominance, while the posterior insula is linked to a relative cardio-sympathetic dominance. These findings provide a deeper understanding of the neural modulation of cardio-autonomic balance, and may have implications for the prevention and treatment of cardio-autonomic dysfunction in neurological disorders.

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Publication Details

Journal
Circulation Arrhythmia and Electrophysiology
Published
2026-02-23
DOI
https://doi.org/10.1161/circep.125.013875
Primary Topic
Heart Rate Variability and Autonomic Control
Type
article
Field-Weighted Citation Impact
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article

Distinct Subdivisions of the Cingulo-Insular Region and Their Role in Modulating the Cardiac Sympathetic-Parasympathetic Balance

Y. Li, Liang Qiao, X. Wang, Na Pan et al.
Circulation Arrhythmia and Electrophysiology
Heart Rate Variability and Autonomic Control
article

Distinct Subdivisions of the Cingulo-Insular Region and Their Role in Modulating the Cardiac Sympathetic-Parasympathetic Balance

Y. Li, Liang Qiao, X. Wang, Na Pan, Yuping Wang, Wei Shu, Cuiping Xu, Tao Yu
article en

Abstract

Within the cingulo-insular region, the anterior cingulate gyrus is associated with a relative cardio-parasympathetic dominance, while the posterior insula is linked to a relative cardio-sympathetic dominance. These findings provide a deeper understanding of the neural modulation of cardio-autonomic balance, and may have implications for the prevention and treatment of cardio-autonomic dysfunction in neurological disorders.

Circulation Arrhythmia and ElectrophysiologyVol. 19(3)
Hebei Medical University (CN), World Wide Web Consortium (US), Chinese Institute for Brain Research (CN), Beijing Xuanwu Traditional Chinese Medicine Hospital (CN), First Affiliated Hospital of Hebei Medical University (CN), International Neuromodulation Society (US), Hebei Science and Technology Department (CN)
Good health and well-being
Openalex Percentile: Top 50%
Heart Rate Variability and Autonomic Control
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