Prognostic Value of a Semi-Quantitative Score Based on 123I-MIBG SPECT/CT in Pediatric Patients With Stage 4 High-Risk Neuroblastoma After Induction Therapy
This study demonstrates that the Curie score derived from 123I-MIBG SPECT/CT imaging after induction therapy is strongly associated with the prognosis of pediatric patients with MIBG-avid stage 4 high-risk neuroblastoma. Notably, patients achieving a Curie score of 6 or lower after induction therapy may benefit from subsequent consolidation and maintenance treatment strategies.
Authors
- Xiaoya Wang (ORCID: https://orcid.org/0000-0002-2860-0003)
- Yi Kan (ORCID: https://orcid.org/0009-0008-9041-136X)
- Jigang Yang (ORCID: https://orcid.org/0000-0002-0538-7676)
- Ziang Zhou (ORCID: https://orcid.org/0009-0008-9662-1456)
- Keyu Zhang
- Guanyun Wang
Institutions
- National Natural Science Foundation of China (CN)
- Capital Medical University (CN)
- Beijing Friendship Hospital (CN)
Publication Details
- Journal
- Clinical Nuclear Medicine
- Published
- 2026-02-13
- DOI
- https://doi.org/10.1097/rlu.0000000000006372
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00