Artificial Intelligence-Enabled ECG Analysis to Predict Incident Heart Failure

ECG2HF is a publicly available 12-lead ECG-based artificial intelligence model that discriminates the risk of future HF with favorable and consistent performance across 3 large health care samples from the northeastern United States. ECG2HF may enable efficient prioritization of high-risk individuals for HF-related preventive measures.

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Publication Details

Journal
Circulation Heart Failure
Published
2026-02-23
DOI
https://doi.org/10.1161/circheartfailure.125.013927
Primary Topic
ECG Monitoring and Analysis
Type
article
Field-Weighted Citation Impact
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article

Artificial Intelligence-Enabled ECG Analysis to Predict Incident Heart Failure

Christopher Reeder, Leah Kosyakovsky, Athar Roshandelpoor, Mitra Chitsazan et al.
Circulation Heart Failure
ECG Monitoring and Analysis
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Artificial Intelligence-Enabled ECG Analysis to Predict Incident Heart Failure

Christopher Reeder, Leah Kosyakovsky, Athar Roshandelpoor, Mitra Chitsazan, Daniel Pipilas, Mahnaz Maddah, Navid A. Nafissi, Shaan Khurshid, J T Ramo, Jonathan W. Waks, Jennifer E. Ho, Mostafa Amer Al-Alusi, S Kany, Valentina D’Souza, Steven A. Lubitz, Patrick T. Ellinor, Emily S. Lau, Anthony A. Philippakis, Pulkit Singh
article en

Abstract

ECG2HF is a publicly available 12-lead ECG-based artificial intelligence model that discriminates the risk of future HF with favorable and consistent performance across 3 large health care samples from the northeastern United States. ECG2HF may enable efficient prioritization of high-risk individuals for HF-related preventive measures.

Circulation Heart Failure
Broad Institute (US), Brigham and Women's Hospital (US), Beth Israel Deaconess Medical Center (US), Harvard University (US), Universität Hamburg (DE), University of California, San Francisco (US), Boston Foundation (US), Massachusetts General Hospital (US), University Medical Center Hamburg-Eppendorf (DE), Institute of Human Genetics (PL), Institute for Molecular Medicine Finland (FI)
Gender equality
Openalex Percentile: Top 50%
ECG Monitoring and Analysis
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