Treatment outcomes in symptomatic Dientamoeba fragilis infection: a prospective clinical and molecular study

DF should be considered in patients with unexplained chronic gastrointestinal symptoms. Molecular testing is recommended for accurate diagnosis. Paromomycin appears to be the most effective treatment, with a strong association between clinical recovery and microbiological cure. Randomized controlled trials are warranted to further define optimal management strategies for DF infection.

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Publication Details

Journal
Infection
Published
2026-02-23
DOI
https://doi.org/10.1007/s15010-026-02746-6
Primary Topic
Parasitic Infections and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
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article

Treatment outcomes in symptomatic Dientamoeba fragilis infection: a prospective clinical and molecular study

Asaf Biber, Eli Schwartz, Dafna Yahav
Infection
Parasitic Infections and Diagnostics
article

Treatment outcomes in symptomatic Dientamoeba fragilis infection: a prospective clinical and molecular study

Asaf Biber, Eli Schwartz, Dafna Yahav
article en

Abstract

DF should be considered in patients with unexplained chronic gastrointestinal symptoms. Molecular testing is recommended for accurate diagnosis. Paromomycin appears to be the most effective treatment, with a strong association between clinical recovery and microbiological cure. Randomized controlled trials are warranted to further define optimal management strategies for DF infection.

Infection
Tel Aviv University (IL), Sheba Medical Center (IL)
Good health and well-being
Openalex Percentile: Top 43%
Parasitic Infections and Diagnostics
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