Design and rationale of the COMPARE-TAVI 2 trial: An all-comers head-to-head comparison of Evolut FX+ and Sapien 3 Ultra Resilia transcatheter heart valves

The COMPARE-TAVI 2 will provide important information on the short- and long-term outcomes among patients treated with the Evolut FX+ self-expandable and the Sapien 3 Ultra Resilia balloon-expandable THVs.

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Publication Details

Journal
American Heart Journal
Published
2026-02-23
DOI
https://doi.org/10.1016/j.ahj.2026.107387
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
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article

Design and rationale of the COMPARE-TAVI 2 trial: An all-comers head-to-head comparison of Evolut FX+ and Sapien 3 Ultra Resilia transcatheter heart valves

Henrik Vase, Henrik Dahl Nissen, Mikko Jalanko, Pertti Jääskeläinen et al.
American Heart Journal
Cardiac Valve Diseases and Treatments
article

Design and rationale of the COMPARE-TAVI 2 trial: An all-comers head-to-head comparison of Evolut FX+ and Sapien 3 Ultra Resilia transcatheter heart valves

Henrik Vase, Henrik Dahl Nissen, Mikko Jalanko, Pertti Jääskeläinen, Rebekka Vibjerg Jensen, Matti Niemelä, Ashkan Eftekhari, Henrik Toft Sørensen, Christian Alcaraz Frederiksen, Christian Juhl Terkelsen, Lars Pedersen, Mikko Savontaus, Mark Hensey, Bjarne Linde Nørgaard, Evald Høj Christiansen
article en

Abstract

The COMPARE-TAVI 2 will provide important information on the short- and long-term outcomes among patients treated with the Evolut FX+ self-expandable and the Sapien 3 Ultra Resilia balloon-expandable THVs.

American Heart JournalVol. 297
Oulu University Hospital (FI), Aalborg University Hospital (DK), Helsinki University Hospital (FI), Odense University Hospital (DK), Turku University Hospital (FI), Aarhus University Hospital (DK), Kuopio University Hospital (FI), St. James's Hospital (IE)
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Openalex Percentile: Top 50%
Cardiac Valve Diseases and Treatments
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