Molecular epidemiology of the expression of urokinase plasminogen activator receptor-associated protein (uPARAP) in mesenchymal malignancies

In conclusion, this study highlights the potential of uPARAP as an innovative target for targeted treatments, such as novel antibody-drug conjugates in sarcoma.

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Publication Details

Journal
Translational Oncology
Published
2026-02-23
DOI
https://doi.org/10.1016/j.tranon.2026.102708
Primary Topic
Protease and Inhibitor Mechanisms
Type
article
Field-Weighted Citation Impact
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article

Molecular epidemiology of the expression of urokinase plasminogen activator receptor-associated protein (uPARAP) in mesenchymal malignancies

Pernille Barkholt, Dominik Mumberg, Kimberly Verbeeck, Ulla Vanleeuw et al.
Translational Oncology
Protease and Inhibitor Mechanisms
article

Molecular epidemiology of the expression of urokinase plasminogen activator receptor-associated protein (uPARAP) in mesenchymal malignancies

Pernille Barkholt, Dominik Mumberg, Kimberly Verbeeck, Ulla Vanleeuw, Lore De Cock, Luna De Sutter, Agnieszka Woźniak, Carmel M. Lynch, Che-Jui Lee, Lars Henning Engelholm, Chao-Chi Wang, Patrick Schöffski
article en

Abstract

In conclusion, this study highlights the potential of uPARAP as an innovative target for targeted treatments, such as novel antibody-drug conjugates in sarcoma.

Translational OncologyVol. 66
VIB-KU Leuven Center for Cancer Biology (BE), Ascendis Pharma (Denmark) (DK), KU Leuven (BE)
Good health and well-being
Openalex Percentile: Top 44%
Protease and Inhibitor Mechanisms
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