CLEC3A-derived peptides exhibit broad-spectrum activity against Candida auris and clinically relevant pathogens
CLEC3A-derived peptides HT-47 and WRK-30 exhibit potent and comparable antibacterial and antifungal activity, highlighting their potential as therapeutic candidates for combating multidrug-resistant pathogens, including <i>C. auris</i>.
Authors
- Gabriele Hermes
- Dzemal Elezagic (ORCID: https://orcid.org/0000-0003-1041-8470)
- Andreas R. Klatt (ORCID: https://orcid.org/0000-0002-8517-7512)
- Jens Ole Beckers
- M Simon
- Jonathan Jantsch (ORCID: https://orcid.org/0000-0001-6944-2913)
- Thomas Streichert (ORCID: https://orcid.org/0000-0002-6588-720X)
- Tamara Rügamer
- Matthias Mörgelin
- Katinka Mies
Institutions
- University of Cologne (DE)
- University Hospital Regensburg (DE)
- St. Marien Hospital (DE)
- Institute of Medical Microbiology and Hygiene (DE)
- University Hospital Cologne (DE)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2026-02-23
- DOI
- https://doi.org/10.3389/fcimb.2026.1756518
- Primary Topic
- Antimicrobial Peptides and Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.00