Podiatric Care Associated with Reduced Mortality and Enhanced Amputation-Free Survival

<b>Background</b>: Diabetic foot ulcers (DFUs) and lower-extremity amputations (LEAs) complicating diabetes mellitus are significant contributors to morbidity, mortality, and disease burden. There is insufficient evidence, however, linking podiatric care to mortality and healthcare resource use. There is, concurrently, inadequate access to podiatric care, particularly in Asia. This study evaluated the clinical and healthcare use outcomes of patients with DFUs who received podiatric care. <b>Methods</b>: A longitudinal study involving patients in Diabetic Foot in Primary and Tertiary (DEFINITE) Care followed over a period of 2 years reviewed the effectiveness of podiatric care with regard to 1-year outcomes using multiple logistic and zero-inflated negative binomial regressions, adjusting for covariates. Clinical outcomes were minor and major LEA, mortality, and LEA-free survival rates; healthcare use outcomes were the number of admissions, number of visits to clinics and emergency departments, and length of stay. <b>Results</b>: Eligible patients (<i>n</i> = 2798 [65.5%]) completed at least 12 months of follow-up. Comparisons were made with patients without access to podiatric care. The overall mean ± SD patient age was 65.7 ± 12.7 years. Most patients receiving podiatric follow-up were of Malay or Indian ethnicities and had poor diabetic control and chronic kidney disease. There were more admissions (<i>p</i> < 0.01) and visits to the emergency department (<i>p</i> < 0.01) and hospital outpatient clinics (<i>p</i> < 0.01), but a shorter length of stay (incidence rate ratio, 0.833; <i>p</i> < 0.01), without any reported differences regarding visits to public primary care clinics (<i>p</i> = 0.68). There were more minor LEAs (<i>p</i> < 0.01) but fewer deaths (<i>p</i> < 0.01) and greater LEA-free survival (odds ratio, 1.26; <i>p</i> = 0.02). <b>Conclusions</b>: Podiatric care improved clinical outcomes for patients with DFU, particularly in terms of LEA-free survival, with a positive impact on healthcare utilization. This is a crucial contribution to the limited evidence on podiatric care in diabetic limb salvage in Asian populations.

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Publication Details

Journal
Journal of the American Podiatric Medical Association
Published
2026-02-23
DOI
https://doi.org/10.3390/japma116010011
Primary Topic
Diabetic Foot Ulcer Assessment and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Podiatric Care Associated with Reduced Mortality and Enhanced Amputation-Free Survival

Chelsea Law, Tiffany Chew, Jeremy Hoe, Elaine Tan et al.
Journal of the American Podiatric Medical Association
Diabetic Foot Ulcer Assessment and Management
article

Podiatric Care Associated with Reduced Mortality and Enhanced Amputation-Free Survival

Chelsea Law, Tiffany Chew, Jeremy Hoe, Elaine Tan, Lixia Ge, Wen Zhe Leo, Huiling Liew, Jo Ann Lim, Zhiwen Joseph Lo, Jaime Lin
article en

Abstract

<b>Background</b>: Diabetic foot ulcers (DFUs) and lower-extremity amputations (LEAs) complicating diabetes mellitus are significant contributors to morbidity, mortality, and disease burden. There is insufficient evidence, however, linking podiatric care to mortality and healthcare resource use. There is, concurrently, inadequate access to podiatric care, particularly in Asia. This study evaluated the clinical and healthcare use outcomes of patients with DFUs who received podiatric care. <b>Methods</b>: A longitudinal study involving patients in Diabetic Foot in Primary and Tertiary (DEFINITE) Care followed over a period of 2 years reviewed the effectiveness of podiatric care with regard to 1-year outcomes using multiple logistic and zero-inflated negative binomial regressions, adjusting for covariates. Clinical outcomes were minor and major LEA, mortality, and LEA-free survival rates; healthcare use outcomes were the number of admissions, number of visits to clinics and emergency departments, and length of stay. <b>Results</b>: Eligible patients (<i>n</i> = 2798 [65.5%]) completed at least 12 months of follow-up. Comparisons were made with patients without access to podiatric care. The overall mean ± SD patient age was 65.7 ± 12.7 years. Most patients receiving podiatric follow-up were of Malay or Indian ethnicities and had poor diabetic control and chronic kidney disease. There were more admissions (<i>p</i> < 0.01) and visits to the emergency department (<i>p</i> < 0.01) and hospital outpatient clinics (<i>p</i> < 0.01), but a shorter length of stay (incidence rate ratio, 0.833; <i>p</i> < 0.01), without any reported differences regarding visits to public primary care clinics (<i>p</i> = 0.68). There were more minor LEAs (<i>p</i> < 0.01) but fewer deaths (<i>p</i> < 0.01) and greater LEA-free survival (odds ratio, 1.26; <i>p</i> = 0.02). <b>Conclusions</b>: Podiatric care improved clinical outcomes for patients with DFU, particularly in terms of LEA-free survival, with a positive impact on healthcare utilization. This is a crucial contribution to the limited evidence on podiatric care in diabetic limb salvage in Asian populations.

Journal of the American Podiatric Medical AssociationVol. 116(1)
Tan Tock Seng Hospital (SG), Khoo Teck Puat Hospital (SG), SingHealth Polyclinics (SG), Woodlands Health Campus (SG), National University Health System (SG)
Agency for Science, Technology and Research, National Healthcare Group, Medical Research Council, National Medical Research Council
Good health and well-being
Openalex Percentile: Top 47%
Diabetic Foot Ulcer Assessment and Management
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