Spatial resolution and image quality of radionuclides for PET imaging
This study demonstrates that the physical properties of radionuclides, particularly positron energy, significantly affected PET image quality, spatial resolution, and saturation thresholds. Lower-energy radionuclides like <sup>18</sup>F and <sup>52</sup>Mn are optimal for high-resolution applications, while higher energy radionuclides are better suited for high-activity imaging. These findings provide valuable guidance for optimizing radionuclide selection in preclinical and clinical PET imaging studies.
Authors
- Shelbie Jaylene Cingoranelli (ORCID: https://orcid.org/0009-0002-5578-0342)
- Sharon Samuel (ORCID: https://orcid.org/0000-0002-5211-0661)
- Yun Lu (ORCID: https://orcid.org/0000-0001-9332-6832)
- Solana Fernandez
- Jennifer M. Pyles (ORCID: https://orcid.org/0000-0001-9049-4275)
- Anna G. Sorace (ORCID: https://orcid.org/0000-0002-3640-3966)
- Hailey A. Houson (ORCID: https://orcid.org/0000-0001-8566-2369)
- Suzanne E. Lapi (ORCID: https://orcid.org/0000-0003-0090-0191)
- Jennifer L. Bartels (ORCID: https://orcid.org/0000-0002-0137-2397)
- Brian D. Wright
- Norio Yasui
Institutions
- University of Alabama at Birmingham (US)
Publication Details
- Journal
- Nuclear Medicine and Biology
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1016/j.nucmedbio.2026.109612
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00